Olidia® is an advanced injectable dermal filler that utilizes Poly-L-Lactic Acid (PLLA) powder as its primary active ingredient. This product is designed to stimulate collagen production in the skin, which is crucial for maintaining skin elasticity and volume. As we age, collagen levels naturally decline, leading to sagging skin and the formation of wrinkles. Olidia® aims to counteract these effects by promoting the body’s own collagen synthesis.

Mechanism of Action

The key component of Olidia® is Poly-L-Lactic Acid (PLLA), a biodegradable material that has been approved by the FDA for use in medical applications. When injected into the dermis, PLLA microparticles stimulate fibroblasts, which are cells responsible for producing collagen. The particle size of PLLA in Olidia® ranges from 40 to 63 micrometers, which is optimal for avoiding phagocytosis by macrophages while still being injectable with fine needles.

Indications for Use

Olidia® is indicated for various aesthetic treatments, including:

• Treatment of severe facial wrinkles and folds
• Restoration of lost facial volume
• Correction of facial lipoatrophy (loss of fat in the face)
• Improvement of facial contour deformities
• Rejuvenation of hands and neck
• Enhancement of scar appearance

Preparation and Administration

Before administering Olidia®, it is essential to properly dilute the solution according to established guidelines. The recommended dilution involves mixing 1 vial (5ml) of Olidia® with 7ml of saline solution and 2ml of lidocaine, resulting in a total volume suitable for multiple syringes. The preferred injection technique is linear threading, which allows for precise placement within the dermis.

Storage Requirements

To maintain its efficacy, Olidia® should be stored at room temperature below 30℃ and must not be frozen. Proper storage conditions are vital to preserve the integrity and effectiveness of the product until it is ready for use.